The Overlooked Benefits of Fucoidan
In the realms of modern beauty and nutrition, Oligo Fucoidan, a sulfated polysaccharide derived from brown seaweed, is gaining significant attention. Due to its diverse biological activities and potential health benefits, Seaweed Fucoidan is rapidly being embraced by both scientists and consumers.
Sources and Characteristics of Fucoidan
Oligo Fucoidan is primarily found in brown seaweeds such as Laminaria (kelp) and Undaria pinnatifida (wakame). These polysaccharides feature highly branched structures and typically contain sulfate and acetyl groups, which contribute to their unique biological activities.
Health Benefits and Applications
Research indicates that Fucoidan offers various health benefits, including antiviral, anti-tumor, immune-modulating, and anti-inflammatory effects. For instance, positive synergistic cytotoxic effects of fucoidan combined with cisplatin on both LLC1 mouse lung carcinoma cells and mice have been reported. A role of the Smurf2-dependent ubiquitin‒proteasome pathway in TGF receptor degradation has been proposed. Fucoidan upregulates TLR4/CHOP-mediated caspase-3 and PARP activation and enhances cisplatin-induced cytotoxicity in human lung cancer cells. Moreover, in human clinical studies, combined cisplatin and fucoidan treatment effectively increased the survival rate of patients with lung cancer in Taiwan. The results indicated that fucoidan exerts a greater anti-tumorigenic effect as an adjuvant, second-line anti-cancer diet supplement and may also regulate immune functions, while cisplatin remains a first-line anti-cancer drug for chemotherapy in clinical human lung cancer treatment.
Beauty and Skincare
In the beauty and skincare industry, Fucoidan is noted for its ability to promote the proliferation of skin fibroblasts and collagen deposition. These properties help improve skin elasticity and thickness, reducing wrinkles and fine lines. Moreover, Fucoidan can inhibit the activity of matrix metalloproteinases (such as collagenase) and tyrosinase, indicating its potential in anti-aging and skin-whitening products.
Conclusion
Fucoidan is a natural ingredient with substantial untapped potential. As more research is conducted and applications are developed, Fucoidan is poised to play a greater role in the beauty and health industries, offering numerous benefits.
Reference:
https://img.cosmeticsandtoiletries.com/files/base/allured/all/image/2019/09/ct.CT_122_08_055_07.pdf
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